Anti-Kinesin-Like Protein (KiF20B) [10C7] Antibody
![Anti-Kinesin-Like Protein (KiF20B) [10C7] Antibody](https://www.kerafast.com/MediaStorage/Product/Images/Large/1046_2001202001263210450.jpg "Anti-Kinesin-Like Protein (KiF20B) [10C7] Antibody")
This mouse IgG1 monoclonal antibody was raised against amino acids 1732 to 1747 of Human Kinesin Family Member 20B (KIF20B) and recognizes KIF20B.
Highlights:
- Reacts with KIF20B
- Suitable for Immunocytochemistry, Indirect Immunofluorescence and Western Blot applications
KIF20B (Kinesin Family Member 20B) is a plus-end-directed motor enzyme that is required for completion of cytokinesis. Diseases associated with KIF20B include Bladder Cancer and Primary Autosomal Recessive Microcephaly. Among its related pathways are Golgi-to-ER retrograde transport and Gastric Cancer Network 1. Gene Ontology (GO) annotations related to this gene include ATPase activity and microtubule motor activity.
From the laboratory of Marvin J. Fritzler, MD, PhD, University of Calgary.
This mouse IgG1 monoclonal antibody was raised against amino acids 1732 to 1747 of Human Kinesin Family Member 20B (KIF20B) and recognizes KIF20B.
Highlights:
- Reacts with KIF20B
- Suitable for Immunocytochemistry, Indirect Immunofluorescence and Western Blot applications
KIF20B (Kinesin Family Member 20B) is a plus-end-directed motor enzyme that is required for completion of cytokinesis. Diseases associated with KIF20B include Bladder Cancer and Primary Autosomal Recessive Microcephaly. Among its related pathways are Golgi-to-ER retrograde transport and Gastric Cancer Network 1. Gene Ontology (GO) annotations related to this gene include ATPase activity and microtubule motor activity.
From the laboratory of Marvin J. Fritzler, MD, PhD, University of Calgary.
Specifications
| Product Type: | Antibody |
| Alternative Name(s): | M-phase phosphoprotein 1 (MPP-1) |
| Antigen: | Kinesin Family Member 20B |
| Accession ID: | Q96Q89 |
| Isotype: | IgG1 |
| Clonality: | Monoclonal |
| Clone Name: | 10C7 |
| Reactivity: | Human and monkey (Other species not tested) |
| Immunogen: | Corresponds to amino acids 1732 to 1747 of Human KIF20B (QPKRAKRKLYTSEISS) |
| Species Immunized: | Mouse |
| Purification Method: | Protein G |
| Buffer: | PBS, 0.05% (w/v) Sodium Azide |
| Positive Control: | This antibody gives a distinctive positive indirect immunofluorescence signal on cell lines: Hela, HEK293T, HEWp2, human leptomeningeal pericyte cell line U2Os |
| Cell lines tested: | Human/mammalian cell lines, cerebellum, ovary and testis, Localize to G2-M phase mammalian nuclei, intercellular bridge |
| Tested Applications: | WB, Immunocytochemistry, Indirect Immunofluorescence |
| Storage: | -20C |
| Shipped: | Cold Packs |
Data
Provider
From the laboratory of Marvin J. Fritzler, MD, PhD, University of Calgary.
References
- Westendorf JM, Rao PN, Gerace L. Cloning of cDNAs for M-phase phosphoproteins recognized by the MPM2 monoclonal antibody and determination of the phosphorylated epitope. Proc Natl Acad Sci USA 1994;91:714-8.
- Fritzler MJ, Kerfoot SM, Feasby TE, Zochodne DW, Westendorf JM, Dalmau JO et al. Autoantibodies from patients with idiopathic ataxia bind to M-phase phosphoprotein 1 (MPP-1). J Invest Med 2000;48:28-39.
- Matsumoto-Taniura N, Priollet F, Monroe R, Gerace L, Westendorf JM. Identification of novel M phase phosphoproteins by expression cloning. Mol Biol Cell 1996;7:1455-69.
- Abaza A, Soleilhac JM, Westendorf J, Piel M, Crevel I, Roux A et al. M phase phosphoprotein 1 is a human plus-end-directed kinesin-related protein required for cytokinesis. J Biol Chem 2003;278:27844-52.
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