Anti-IL-2RB (CD122) [5H4] Antibody

This rat IgG2a monoclonal antibody was raised against rat YB2/0 cell line expressing truncated IL-2Rβ and is specific for mouse Interleukin 2 receptor beta chain (IL-2Rβ).

Highlights:

  • Reacts with mouse IL-2Rβ

The 5H4 antibody reacts with mouse CD122, the 90-110 kDa interleukin-2 receptor beta chain. CD122 is expressed by NK cells and some T cells in the periphery and is upregulated by activation. CD122 associates with CD25 and CD132 (common gamma chain) to form the high affinity IL-2 receptor. Binding of IL-2 to CD122 is not inhibited by the 5H4 antibody.

From the laboratory of Thomas R. Malek, PhD, University of Miami.

Catalog Number Product Size AVAILABILITY Price Qty
EMI024
Anti-IL-2RB (CD122) [5H4] Antibody
100ug 3-5 weeks
Regular Price:$299.00
Specifications

Product Type: Antibody
Antigen: IL-2Rβ
Molecular Weight: 70-85kDa
Isotype: IgG2a
Clonality: Monoclonal
Clone Name: 5H4
Reactivity: Mouse
Species Immunized: Lewis Rat
Purification Method: Protein G
Buffer: 0.1M Sodium Phosphate, pH 7.4, 0.15M NaCl, 0.05% (w/v) Sodium Azide
Storage: -20C
Shipped: Cold Packs

Provider
From the laboratory of Thomas R. Malek, PhD, University of Miami.

References
  1. Malek TR, Furse RK, Fleming ML, Fadell AJ, He YW. Biochemical identity and characterization of the mouse interleukin-2 receptor beta and gamma c subunits. J Interferon Cytokine Res. 1995 May;15(5):447-54. PubMed PMID: 7648447.

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