Anti-IgE [R1E4] Antibody
![Anti-IgE [R1E4] Antibody](https://www.kerafast.com/MediaStorage/Product/Images/Large/1247_2001202001264012460.jpg "Anti-IgE [R1E4] Antibody")
This rat IgG1 monoclonal antibody was generated against immunoglobulin E (IgE) in adjuvant and recognizes mouse Fc of IgE.
Highlights:
- Reacts with mouse IgE (epitope: Fc)
- Blocks IgE binding to mouse or rat FceRI
- Suitable for ELISA applications
Recombinant versions available at our sister company, Absolute Antibody:
- Clone R1E4 available in various species, isotope and/or format
- Manufactured using Absolute Antibody’s Recombinant Platform with variable regions (i.e., specificity) from the hybridoma R1E4
Immunoglobulin E is an antibody only found in mammals and its main function is immunity against parasites. IgE also has an essential role in type I hypersensitivity, such as allergic asthma, sinusitis, allergic rhinitis, food allergies, and specific types of chronic urticaria and atopic dermatitis.
From the laboratory of Daniel H. Conrad, PhD, Virginia Commonwealth University.
This rat IgG1 monoclonal antibody was generated against immunoglobulin E (IgE) in adjuvant and recognizes mouse Fc of IgE.
Highlights:
- Reacts with mouse IgE (epitope: Fc)
- Blocks IgE binding to mouse or rat FceRI
- Suitable for ELISA applications
Recombinant versions available at our sister company, Absolute Antibody:
- Clone R1E4 available in various species, isotope and/or format
- Manufactured using Absolute Antibody’s Recombinant Platform with variable regions (i.e., specificity) from the hybridoma R1E4
Immunoglobulin E is an antibody only found in mammals and its main function is immunity against parasites. IgE also has an essential role in type I hypersensitivity, such as allergic asthma, sinusitis, allergic rhinitis, food allergies, and specific types of chronic urticaria and atopic dermatitis.
From the laboratory of Daniel H. Conrad, PhD, Virginia Commonwealth University.
Specifications
| Product Type: | Antibody |
| Antigen: | Mouse IgE |
| Molecular Weight: | 190 kDa |
| Isotype: | IgG1 |
| Clonality: | Monoclonal |
| Clone Name: | R1E4 |
| Reactivity: | Mouse |
| Immunogen: | IgE in adjuvant |
| Species Immunized: | Rat |
| Epitope: | Fc |
| Purification Method: | Protein G |
| Buffer: | 0.1M Sodium Phosphate, pH 7.4, 0.15M NaCl, 0.05% (w/v) Sodium Azide |
| Tested Applications: | ELISA |
| Storage: | -20C |
| Shipped: | Cold packs |
Provider
From the laboratory of Daniel H. Conrad, PhD, Virginia Commonwealth University.
References
- Keegan AD, Fratazzi C, Shopes B, Baird B, Conrad DH. Characterization of new rat anti-mouse IgE monoclonals and their use along with chimeric IgE to further define the site that interacts with Fc epsilon RII and Fc epsilon RI. Mol Immunol. 1991 Oct;28(10):1149-54.
If you publish research with this product, please let us know so we can cite your paper.
