Lianchun Wang, MD, University of Georgia*

Lianchun Wang, MD

*Now affiliated with University of South Florida.

The Wang laboratory primary research interest is to understand the role and the underlying mechanisms of heparan sulfate proteoglycans in angiogenesis, stem cell, hemostasis and leukoctye trafficking/inflammation with a long-term goal to develop novel therapeutics to improve the treatment of vascular diseases such as ischemia and stroke, inflamation and cancer et al.

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References

  1. Qiu H, Shi S, Yue J, et al. A mutant-cell library for systematic analysis of heparan sulfate structure-function relationships. Nat Methods. 2018;15(11):889-899.
  2. Capicciotti CJ, Zong C, Sheikh MO, Sun T, Wells L, Boons GJ. Cell-Surface Glyco-Engineering by Exogenous Enzymatic Transfer Using a Bifunctional CMP-Neu5Ac Derivative. J Am Chem Soc. 2017;139(38):13342-13348.
  3. Guo C, Fan X, Qiu H, Xiao W, Wang L, Xu B. High-resolution probing heparan sulfate-antithrombin interaction on a single endothelial cell surface: single-molecule AFM studies. Phys Chem Chem Phys. 2015;17(20):13301-13306.
  4. Qiu H, Jiang JL, Liu M, Huang X, Ding SJ, Wang L. Quantitative phosphoproteomics analysis reveals broad regulatory role of heparan sulfate on endothelial signaling. Mol Cell Proteomics. 2013;12(8):2160-2173.