Human STAT3, rSTAT3-80

Recombinant human STAT3 protein, produced from E. coli.

The Signal transducer and activator of transcription 3 (STAT 3), functions as a cytoplasmic mediator of cytokine signaling and nuclear transcription factor. STAT3 is considered as one of the most crucial member of the STAT family. STAT3 activation occurs via the phosphorylation of tyrosine residue (Y705) by JAK (Janus Kinase) and serine (S727) by MAPK and non-receptor tyrosine kinases. In particular STAT 3 activity is detected in a wide variety of tumors, driving multiple pro-oncogenic functions.

Catalog Number Product DataSheet Size AVAILABILITY Price Qty
FGN016
Human STAT3, rSTAT3-80
100ug 4-6 weeks
Regular Price:$410.00
On Sale:
FGN017
Human STAT3, rSTAT3-80
500ug 4-6 weeks
Regular Price:$815.00
On Sale:
FGN018
Human STAT3, rSTAT3-80
1mg 4-6 weeks
Regular Price:$1,420.00
On Sale:
Specifications

Product Type: Protein
Name: Human STAT3
Alternative Name(s): Signal transducer and activator of transcription 3, STAT3
Accession ID: P40763
Source: Human Ð expressed in E. coli
Molecular Weight: 82.4 kDa
Amino Acid Sequence: MAQWNQLQQL DTRYLEQLHQ LYSDSFPMEL RQFLAPWIES QDWAYAASKE SHATLVFHNL LGEIDQQYSR FLQESNVLYQ HNLRRIKQFL QSRYLEKPME IARIVARCLW EESRLLQTAA TAAQQGGQAN HPTAAVVTEK QQMLEQHLQD VRKRVQDLEQ KMKVVENLQD DFDFNYKTLK SQGDMQDLNG NNQSVTRQKM QQLEQMLTAL DQMRRSIVSE LAGLLSAMEY VQKTLTDEELADWKRRQQIA CIGGPPNICL DRLENWITSL AESQLQTRQQ IKKLEELQQK VSYKGDPIVQ HRPMLEERIV ELFRNLMKSA FVVERQPCMP MHPDRPLVIK TGVQFTTKVR LLVKFPELNY QLKIKVCIDK DSGDVAALRG SRKFNILGTN TKVMNMEESN NGSLSAEFKH LTLREQRCGN GGRANCDASL IVTEELHLIT FETEVYHQGL KIDLETHSLP VVVISNICQM PNAWASILWY NMLTNNPKNV NFFTKPPIGT WDQVAEVLSW QFSSTTKRGL SIEQLTTLAE KLLGPGVNYS GCQITWAKFC KENMAGKGFS FWVWLDNIID LVKKYILALW NEGYIMGFIS KERERAILST KPPGTFLLRF SESSKEGGVT FTWVEKDISG KTQIQSVEPY TKQQLNNMSF AEIIMGYKIM DATNILVSPL VYLYPDIPKE EAFGKYCRPE SQEHPEADPG SAAPYLKTKF ICVTPT
Fusion Tag(s): C-terminus 6 _ His tag
Format: Lyophilized powder. Dilute to 1 mg/mL in PBS
Purity: >98 %, purified by Ni NTA and determined by SDS-PAGE.
Buffer: PBS
Tested Applications: Drug discovery, research, cell proliferation assays
Comments: Manufactured in an ISO 9001:20015 Certified Laboratory
Storage: Store at -20 degree C, for extended storage
Shipped: Cold packs

Documentation
Provider
From the laboratory at GeNext Genomics Pvt Ltd.
References

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