Biotin Picolyl Azide
Biotin Picolyl Azide incorporates a copper-chelating group to the azide structure to allow co-diffusion and concentrate copper at the reaction site.
The picolyl azide effect is so strong that it more than compensate for the effect of omitting THPTA ligand or decreasing the Cu concentration from 100 μm to 10 μm. In addition Biotin Picolyl Azide can be used under classic copper-catalyzed click reactions with dramatically increased efficiency.
Biotin Picolyl Azide incorporates a copper-chelating group to the azide structure to allow co-diffusion and concentrate copper at the reaction site.
The picolyl azide effect is so strong that it more than compensate for the effect of omitting THPTA ligand or decreasing the Cu concentration from 100 μm to 10 μm. In addition Biotin Picolyl Azide can be used under classic copper-catalyzed click reactions with dramatically increased efficiency.
| Catalog Number | Product | DataSheet | Size | AVAILABILITY | Price | Qty |
|---|
Specifications
| Product Type: | Small Molecule |
| Chemical Formula: | C27H42N8O7S |
| CAS number: | N/A |
| Molecular Weight: | 622.74 |
| Variant MPN: | 1167 |
| Format: | Off-white to slightly orange amorphous solid |
| Purity: | >95% (HPLC) |
| Solubility: | DMSO, DMF |
| Storage: | -20C. Desiccate |
| Shipped: | Ambient |
Documentation
References
- Jiang, H., et al. (2014). Monitoring Dynamic Glycosylation in Vivo Using Supersensitive Click Chemistry. Bioconjugate Chem., 25(4): 698-706.
- Uttamapinant, C., et al. (2012). Fast, Cell-Compatible Click Chemistry with Copper-Chelating Azides for Biomolecular Labeling. Angew. Chem. Int. Ed,. 51(24): 58525856.
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