Anti-NPC1 [17B5] Antibody

This antibody is specific to a Human NPC1 fragment conjugated to a carrier protein.

Niemann-Pick disease type C1 is a lysosomal storage disease caused by a mutation in the NPC1 gene. NPC1 encodes an integral membrane protein containing sequence motifs thought to be consistent with a role in intracellular transport of cholesterol to post-lysosomal destinations. Mutations in NPC1 have also been linked with obesity, HIV-AIDS, and Ebola virus.

From the laboratory of Yiannis Ioannou, PhD, Icahn School of Medicine at Mount Sinai.

The Investigator's Annexe Part of The Investigator's Annexe program.

Catalog Number Product Size AVAILABILITY Price Qty
EMS004
Anti-NPC1 [17B5] Antibody, 100ug
100ug 2-3 weeks
Price: $283.00
Specifications
Name: Anti NPC1 monoclonal antibody (17B5)
Isotype: IgG1
Clonality: Monoclonal
Clone Name: 17B5
Specificity: This antibody recognizes Human NPC1
Immunogen: Human NPC-1 fragment conjugated to a carrier protein
Host: Mouse
Format: Liquid
Buffer: 0.1M Sodium Phosphate, pH 7.4, 0.15M NaCl, 0.05% (w/v) Sodium Azide
Tested Applications: WB
Purity: Protein G purified
Storage: Store at 4C
Shipped: Cold packs
Provider
From the laboratory of Yiannis Ioannou, PhD, Icahn School of Medicine at Mount Sinai.
References
  1. Davies et al, Transmembrane Molecular Pump Activity of Niemann-Pick C1. Protein Science, 290, 2295, 2000.

If you publish research with this product, please let us know so we can cite your paper.

 
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