Anti-VEGF Receptor Kdrl/FLK-1 Antibody

This rabbit polyclonal antibody was generated against peptide and is specific for zebrafish vascular endothelial growth factor receptor kdr-like (Kdrl).

Highlights:

  • Reacts with zebrafish Kdrl
  • Binds to the cytoplasmic domain of Kdrl
  • Suitable for Whole Mount Immunostaining applications

Kdrl is a receptor for VEGF or VEGFC with tyrosine-protein kinase activity. It's involved in angiogenesis specifically in VEGF-induced sprouting of new blood vessels and artery formation. Many VEGF receptors are required for development of different blood vessel types in the embryo.

From the laboratory of Nathan D. Lawson, PhD, University of Massachusetts Medical School.

Catalog Number Product Size AVAILABILITY Price Qty
ES1003
Anti-VEGF Receptor Kdrl/FLK-1 Antibody, 100uL
100uL In stock
Price: $299.00
Specifications
Product Type: Antibody
Antigen: Kdrl
Accession ID: NP_571547
Molecular Weight: 147 kDa
Clonality: Polyclonal
Reactivity: Zebrafish
Immunogen: Peptide
Species Immunized: Rabbit
Epitope: Cytoplasmic domain
Buffer: Polyclonal serum with 0.02% sodium azide
Tested Applications: Whole mount immunostaining (1:500)
Comments: Recommend aliquotting into small working volumes after initial thaw and store these at -80°C
Storage: -80C
Shipped: Dry Ice
Data

Whole Mount Immunostaining

Whole mount immunostaining of a wild type zebrafish embryo at 24hpf using anti-zebrafish Kdrl antibody. Embryo was immunostained with primary anti-zebrafish Kdrl antibody at 1:5000, followed by detection using 1:5000 ZyMAXTM goat anti-rabbit IgG(H+L)-HRP (Life Technologies) and tyramide-Cy3 amplification. Strong fluorescence is observed in endothelial cells of the intersomitic vessels (indicated by arrows) and the dorsal aorta (DA).

Provider
From the laboratory of Nathan D. Lawson, PhD, University of Massachusetts Medical School.

References

If you publish research with this product, please let us know so we can cite your paper.

 
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