Rat Retinal Pigment Epithelium Cell Line (BPEI-1)

Spontaneously arising cell line of rat pigment epithelial cells (RPE) named BPEI-1 with RPE-specific features.

Highlights:

  • Cells express cytokeratin and cellular retinaldehyde binding protein (RLBP1)
  • Cells have the ability to phagocytize photoreceptor outer segments.

The pigmented layer of retina or retinal pigment epithelium (RPE) is a monolayer of pigmented cells situated between the neuroretina and the choroids. There are a few main functions of the RPE, including transport of nutrients, absorption of light, phagocytosis of shed photoreceptor membranes, and secretion of essential factors for the structural integrity of the retina. Research has shown that the RPE is where macular degeneration begins.

From the laboratory of George Inana, MD, PhD, University of Miami.

Catalog Number Product Size AVAILABILITY Price Qty
EMI013
Rat Retinal Pigment Epithelium Cell Line (BPEI-1), 1 vial
1 vial 3-5 weeks
Price: $499.00
Specifications
Product Type: Cell Line
Cell Type: Retinal pigment epithelium
Organism: Rat
Accession ID: CVCL_DF63
Morphology: Epithelial to fibroblastic
Biosafety Level: BSL 1
Subculturing: Multiple times, 18h doubling time in MEM 20% FBS
Growth Conditions: MEM with 20% FBS or MEM with 5% FBS
Cryopreservation: 10% DMSO and 90% FBS
Source: Rat eye/RPE
Storage: LN2
Shipped: Dry Ice
Provider
From the laboratory of George Inana, MD, PhD, University of Miami.

References
  1. McLaren MJ, Sasabe T, Li CY, Brown ME, Inana G. Spontaneously arising immortal cell line of rat retinal pigmented epithelial cells. Exp Cell Res. 1993 Feb;204(2):311-20.

If you publish research with this product, please let us know so we can cite your paper.

 
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