Anti-Cereblon (CRBN) [3B12F7] Antibody
![Anti-Cereblon (CRBN) [3B12F7] Antibody](https://www.kerafast.com/MediaStorage/Product/Images/Large/1632_2001202001265516310.jpg "Anti-Cereblon (CRBN) [3B12F7] Antibody")
This mouse IgG1k monoclonal antibody was generated against synthetic peptide and recognizes all mammals cereblon (CRBN).
Highlights:
- Reacts with all mammalian CRBNs tested
- Suitable for Western Blot and Immunohistochemistry applications
Protein cereblon is encoded by the CRBN, other names include AD-006 and MRT2A. It was originally identified as a genetic cause of inherited autosomal recessive mental retardation, the gene encodes a substrate receptor of a ubiquitin E3 cullin 4-RING ligase (CRL4) complex. CRBN also may play a role in memory and learning by regulating the assembly and neuronal surface expression of large-conductance calcium-activated potassium channels in brain regions involved in memory and learning by its interaction with KCNT1. Also has been shown to be involved in pathway protein ubiquitination.
From the laboratory of David M. Lucas, PhD, The Ohio State University.
This mouse IgG1k monoclonal antibody was generated against synthetic peptide and recognizes all mammals cereblon (CRBN).
Highlights:
- Reacts with all mammalian CRBNs tested
- Suitable for Western Blot and Immunohistochemistry applications
Protein cereblon is encoded by the CRBN, other names include AD-006 and MRT2A. It was originally identified as a genetic cause of inherited autosomal recessive mental retardation, the gene encodes a substrate receptor of a ubiquitin E3 cullin 4-RING ligase (CRL4) complex. CRBN also may play a role in memory and learning by regulating the assembly and neuronal surface expression of large-conductance calcium-activated potassium channels in brain regions involved in memory and learning by its interaction with KCNT1. Also has been shown to be involved in pathway protein ubiquitination.
From the laboratory of David M. Lucas, PhD, The Ohio State University.
| Product Type: | Antibody |
| Antigen: | Cereblon (CRBN, AD-006, MRT2A) |
| Accession ID: | Q96SW2 |
| Molecular Weight: | 51 kDa |
| Isotype: | IgG1k |
| Clonality: | Monoclonal |
| Clone Name: | 3B12F7 |
| Reactivity: | All mammals |
| Immunogen: | KLH-conjugated linear peptide corresponding to a sequence near the N-terminus of human cereblon |
| Species Immunized: | Mouse |
| Epitope: | Available upon request |
| Purification Method: | Protein G |
| Buffer: | PBS, 0.05% (w/v) Sodium Azide |
| Tested Applications: | WB (1:1000), IHC (1:50) |
| Storage: | -20C |
| Shipped: | Cold Packs |
If you publish research with this product, please let us know so we can cite your paper.
