Anti-Adiopokinetic Hormone (AKH) Antibody

This rabbit polyclonal antibody was generated against Drosophila melanogaster Adiopokinetic Hormone (AKH) and recognizes AKH from Drosophila melanogaster, Aedes aegypti, Anopheles gambiae, and Rhodnius prolixus.

Highlights:

  • Positive results for immunocytochemistry to detect AKH in the nervous system of Drosophila melanogaster, Aedes aegypti, Anopheles gambiae, and Rhodnius prolixus.
  • Suitable for Immunocytochemistry and Immunohistochemistry applications; Works fine for radioimmunoassay, not tested for enzyme immunoassay, and probably not suitable for western blots

Adiopokinetic Hormone (AKH) is a short peptide hormone that has been studied in insects. The neuropeptides that mobilize stored fuels for flight in insects, and thus, may regulate flight by mosquitoes that transmit pathogens of human diseases.

From the laboratory of Mark R. Brown, PhD, University of Georgia.

Catalog Number Product Size AVAILABILITY Price Qty
EGA261
Anti-Adiopokinetic Hormone (AKH) Antibody, 50uL
50uL In stock
Price: $299.00
Specifications
Product Type: Antibody
Antigen: Adiopokinetic Hormone (AKH)
Accession ID: Q27Q78
Molecular Weight: 8.9 kDa
Clonality: Polyclonal
Reactivity: Recognizes both Anopheles AKHs: Anoga-AKH-I (pQLFTPAWa) and Anoga-AKH-II (pQVTFSRDWNAa). Also recognizes AKH from Pe. americana, Drosophila and Rhodnius prolixus (others not tested)
Immunogen: Drosophila melanogaster AKH (pQLTFSPDWa, ~1000 Da) conjugated to porcine thyroglobulin.
Species Immunized: Rabbit
Buffer: Serum
Tested Applications: ICC, IHC
Storage: -80C
Shipped: Dry Ice
Provider
From the laboratory of Mark R. Brown, PhD, University of Georgia.

References
  1. Kaufmann C, Brown MR. Adipokinetic hormones in the African malaria mosquito, Anopheles gambiae: identification and expression of genes for two peptides and a putative receptor. Insect Biochem Mol Biol. 2006 Jun;36(6):466-81. Epub 2006 Apr 7.
  2. Kubrak OI, Lushchak OV, Zandawala M, Nässel DR. Systemic corazonin signalling modulates stress responses and metabolism in Drosophila. Open Biol. 2016 Nov;6(11). pii: 160152.
  3. Kaufmann C, Merzendorfer H, Gäde G. 2009 The adipokinetic hormone system in Culicinae (Diptera: Culicidae): molecular identification and characterization of two adipokinetic hormone (AKH) precursors from Aedes aegypti and Culex pipiens and two putative AKH receptor variants from A. aegypti. Insect Biochem Mol Biol. 39(11):770-81.
  4. Patel H, Orchard I, Veenstra JA, Lange AB. 2014 The distribution and physiological effects of three evolutionarily and sequence-related neuropeptides in Rhodnius prolixus: Adipokinetic hormone, corazonin and adipokinetic hormone/corazonin-related peptide. Gen Comp Endocrinol. 195:1-8.
  5. Patel H, Orchard I, Veenstra JA, Lange AB. The distribution and physiological effects of three evolutionarily and sequence-related neuropeptides in Rhodnius prolixus: Adipokinetic hormone, corazonin and adipokinetic hormone/corazonin-related peptide. Gen Comp Endocrinol. 2014 Jan 1;195:1-8. doi: 10.1016/j.ygcen.2013.10.012. Epub 2013 Oct 31.

If you publish research with this product, please let us know so we can cite your paper.

 
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