Anti-Notch 3 Antibodies

These mouse IgG monoclonal antibodies were generated against human notch 3 (partial, amino acids 807-884) and recognize neurogenic locus notch homolog protein 3 (Notch 3).

Highlights:

  • Reacts with Notch 3
  • These antibodies showed anti-proliferative activities in cancer cells in vitro
  • Suitable for Western Blot applications

Notch 3 protein is part of the Notch superfamily consisting of transmembrane proteins with repeated extracellular EGF domains and the notch domains. The Notch signaling network is an evolutionary conserved intercellular signaling pathway that regulates interactions between physically adjacent cells.  It has shown to be involved in lateral inhibition in embryogenesis. Notch 3 is being investigated as a target for anti-cancer drugs, as it is overexpressed in several types of cancers.

From the laboratory of Thao P. Dang, MD, University of Virginia.

Catalog Number Product Size AVAILABILITY Price Qty
EG1011
Anti-Notch 3 [7G7-B10-H3] Antibody, 100ug
100ug 3-5 weeks
Price: $299.00
EG1012
Anti-Notch 3 [7G7-B10-H7] Antibody, 100ug
100ug 3-5 weeks
Price: $299.00
Specifications
Product Type: Antibody
Alternative Name(s): Notch 3 extracellular truncation, Notch 3 intracellular domain
Antigen: Notch 3
Isotype: IgG
Clonality: Monoclonal
Clone Name: 7G7-B10-H3 or 7G7-B10-H7
Immunogen: Human notch 3 (partial, amino acids 807-884)
Species Immunized: Mouse
Purification Method: Protein G
Buffer: 0.1M Sodium Phosphate, pH 7.4, 0.15M NaCl, 0.05% (w/v) Sodium Azide
Tested Applications: WB
Storage: -20C
Shipped: Cold Packs
Provider
From the laboratory of Thao P. Dang, MD, University of Virginia.

References

If you publish research with this product, please let us know so we can cite your paper.

 
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