ODIBO-EG4-NHS
ODIBO-EG4-NHS for strain-promoted alkyne-azide cycloaddition (SPAAC) applications.
Highlights:
- Reacts with azide 50-100 times faster than DBCO (a.k.a., ADIBO or DIBAC) and 200-400 faster than DIBO.
- Significantly reduces the time required for bio-conjugation and /or allows for conducting SPAAC ligations at much lower concentrations
- Equipped with amine-reactive NHS group for easy derivatization of peptides, proteins, and tissues
- Long shelf life under ambient conditions
- Suitable strain-promoted alkyne-azide cycloaddition (SPAAC), SPANC, SPANOC, IEDDA, and thiol-yne reactions for the cell and tissue labeling, surface modifications, chemical synthesis, triazole synthesis
- Excess of reagent can be conveniently quenched with sodium azide solution
Precursors in the study of strain-promoted alkyne-azide cycloaddition (SPAAC), SPANC, Diels-Alder, and thiol-yne reactions cell and tissue labeling, surface modifiers, chemical synthesis, homo- and hetero-nuclear π metastasis reactions, light-selective labeling, photo-patterning, triazole synthesis, azide quenching reactions.
From the laboratory of Vladimir V. Popik, PhD, University of Georgia.
ODIBO-EG4-NHS for strain-promoted alkyne-azide cycloaddition (SPAAC) applications.
Highlights:
- Reacts with azide 50-100 times faster than DBCO (a.k.a., ADIBO or DIBAC) and 200-400 faster than DIBO.
- Significantly reduces the time required for bio-conjugation and /or allows for conducting SPAAC ligations at much lower concentrations
- Equipped with amine-reactive NHS group for easy derivatization of peptides, proteins, and tissues
- Long shelf life under ambient conditions
- Suitable strain-promoted alkyne-azide cycloaddition (SPAAC), SPANC, SPANOC, IEDDA, and thiol-yne reactions for the cell and tissue labeling, surface modifications, chemical synthesis, triazole synthesis
- Excess of reagent can be conveniently quenched with sodium azide solution
Precursors in the study of strain-promoted alkyne-azide cycloaddition (SPAAC), SPANC, Diels-Alder, and thiol-yne reactions cell and tissue labeling, surface modifiers, chemical synthesis, homo- and hetero-nuclear π metastasis reactions, light-selective labeling, photo-patterning, triazole synthesis, azide quenching reactions.
From the laboratory of Vladimir V. Popik, PhD, University of Georgia.
Specifications
| Product Type: | Small Molecule |
| Name: | ODIBO-EG4-NHS, ODIBO-TEG-NHS |
| Chemical Formula: | C32H9N2O9 |
| Molecular Weight: | 594.66 |
| Format: | viscous liquid / solid |
| Purity: | >99% 1HNMR |
| Solubility: | DMSO, MeOH, ETOH, AcOEt, DCM, CHCl3, THF, MeCN |
| Concentration: | 40mg/2mL in DMSO |
| Spectral Information: | See: Spectral Information |
| Storage: | +10C |
| Shipped: | Ambient Temperature |
Provider
From the laboratory of Vladimir V. Popik, PhD, University of Georgia.
References
- K. Brooks, J Yatvin, C.D. McNitt, RA Reese, C Jung, VV Popik, J Locklin: Multifunctional Surface Manipulation Using Orthogonal Click Chemistry. Langmuir, 2016, 32 (26), 6600–6605
- CD McNitt, V.V. Popik, S Dhar: Copper-Free Click-Chemistry Platform to Functionalize Cisplatin Prodrugs: Chem. Eur. J., 2014, 20 (23), 6861-6865)
- US Patents 8,912,322
If you publish research with this product, please let us know so we can cite your paper.
