Anti-CIB1 [3C5] Antibody

This mouse IgG1k monoclonal antibody was raised against GST fusion protein and recognizes human and mouse calcium and integrin binding protein 1 (CIB1)

Highlights:

  • Recognizes human and mouse CIB1
  • Specific for C-terminal half of CIB1
  • Suitable for Western Blot, Immunoprecipitation and Immunocytochemistry applications

Calcium and integrin binding protein 1 (CIB1) belongs to the calcium-binding protein family and has significant homology to calmodulin and calcineurin B. CIB1 may regulate various cellular processes by associating with proteins such as FAK and PAK1 which are known to regulate angiogenesis. It also may play a role in the regulation of numerous cellular processes, such as cell differentiation, cell division, cell proliferation, cell migration, thrombosis, angiogenesis, cardiac hypertrophy and apoptosis. CIB appers to be a novel Ca2+ binding protein that interacts with the integrin alphaIIb subunit cytoplasmic domain, but not to other integrin cytoplasmic domains. This protein is expressed in platelets and binds to heterodimeric integrin alphaIIb/beta3 (GPIIb/IIIa) as a potential intracellular regulatory molecule.

From the laboratory of Ulhas P. Naik, PhD, Thomas Jefferson University.

Catalog Number Product Size AVAILABILITY Price Qty
ETJ001
Anti-CIB1 [3C5] Antibody, 100ug
100ug 3-5 weeks
Price: $299.00
Specifications
Product Type: Antibody
Name: CIB1 [3C5] Antibody
Alternative Name(s): Calmyrin, DNA-PKcs-interacting protein, DNA-dependent protein kinase interacting protein, Kinase-interacting protein, KIP, SNK-interacting protein 2-28, SIP2-28, calcium and integrin binding protein
Antigen: CIB1
Accession ID: AR157059, U82226, Q99828
Molecular Weight: 22 kDa
Isotype: IgG1k
Clonality: Monoclonal
Clone Name: 3C5
Reactivity: Human and mouse
Immunogen: Recombinant GST fusion protein
Species Immunized: Mouse
Epitope: C-terminal half
Purification Method: Protein G
Buffer: 0.1M Sodium Phosphate, pH 7.4, 0.15M NaCl, 0.05% (w/v) Sodium Azide
Tested Applications: WB (1:1000), IP (5ug/ml), IC
Storage: -20C
Shipped: Cold packs
Provider
From the laboratory of Ulhas P. Naik, PhD, Thomas Jefferson Univseristy.
References

If you publish research with this product, please let us know so we can cite your paper.

 
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