Anti-Dentin Sialophosphoprotein (DSPP), human DSP domain [LF-151] Antibody

This rabbit IgG polyclonal antibody was generated against recombinant protein (E coli) and is specific for human Dentin Sialophosphoprotein (DSPP).

Highlights:

  • Recognizes human DSPP - Epitope T132 to D373 (DSP domain); cross-reacts with cow DSPP
  • Suitable for Immunohistochemistry and Western Blot applications

The two proteins dentin sialoprotein and dentin phosphoprotein are components of dentin, which is a bone-like substance that makes up the protective middle layer of each tooth. Dentin phosphoprotein is thought to be involved in the biomineralization process of dentin. Mutations in this gene have been associated with dentinogenesis imperfecta-1.

From the laboratory of Larry W. Fisher, PhD, National Institute of Dental and Craniofacial Research/NIH.

Catalog Number Product Size AVAILABILITY Price Qty
ENH081
Anti-Dentin Sialophosphoprotein (DSPP), human DSP domain [LF-151] Antibody, 100uL
100uL In stock
Price: $306.00

This product is for sale to Nonprofit customers only. For profit customers, please Contact Us for more information.

Specifications
Antigen: Dentin Sialophosphoprotein (DSPP), human
Accession ID: NP_055023.2
Molecular Weight: 131151 Da
Clonality: Polyclonal
Clone Name: LF-151
Reactivity: human (cross reacts with cow)
Immunogen: Recombinant protein (E. coli)
Species Immunized: Rabbit
Epitope: T132 to D373 (DSP domain)
Buffer: Whole serum
Tested Applications: WB 1:2000, IHC 1:200
Storage: -80C
Shipped: Dry Ice
Provider
From the laboratory of Larry W. Fisher, PhD, National Institute of Dental and Craniofacial Research.
References
  1. Gronthos S, Brahim J, Li W, Fisher LW, Cherman N, Boyde A, DenBesten P, Robey PG, Shi S. Stem cell properties of human dental pulp stem cells. J Dent Res. 2002 Aug;81(8):531-5. PubMed PMID: 12147742.
  2. Ogbureke KU, Abdelsayed RA, Kushner H, Li L, Fisher LW. Two members of the SIBLING family of proteins, DSPP and BSP, may predict the transition of oral epithelial dysplasia to oral squamous cell carcinoma. Cancer. 2010 Apr 1;116(7):1709-17.
  3. Jain A, McKnight DA, Fisher LW, Humphreys EB, Mangold LA, Partin AW, Fedarko NS. Small integrin-binding proteins as serum markers for prostate cancer detection. Clin Cancer Res. 2009 Aug 15;15(16):5199-207.
  4. Miura M, Gronthos S, Zhao M, Lu B, Fisher LW, Robey PG, Shi S. SHED: stem cells from human exfoliated deciduous teeth. Proc Natl Acad Sci U S A. 2003 May 13;100(10):5807-12. Epub 2003 Apr 25. PubMed PMID: 12716973; PubMed Central PMCID: PMC156282.
  5. Srisuwan T, Tilkorn DJ, Al-Benna S, Vashi A, Penington A, Messer HH, Abberton KM, Thompson EW. Survival of rat functional dental pulp cells in vascularized tissue engineering chambers. Tissue Cell. 2012 Apr;44(2):111-21.
  6. Yamauchi N, Nagaoka H, Yamauchi S, Teixeira FB, Miguez P, Yamauchi M. Immunohistological characterization of newly formed tissues after regenerative procedure in immature dog teeth. J Endod. 2011 Dec;37(12):1636-41.
  7. Kereshanan S, Stephenson P, Waddington R. Identification of dentine sialoprotein in gingival crevicular fluid during physiological root resorption and orthodontic tooth movement. Eur J Orthod. 2008 Jun;30(3):307-14.
  8. Sugars RV, Olsson ML, Waddington R, Wendel M. Substitution of bovine dentine sialoprotein with chondroitin sulfate glycosaminoglycan chains. Eur J Oral Sci. 2006 Feb;114(1):89-92. PubMed PMID: 16460347.

If you publish research with this product, please let us know so we can cite your paper.

 
Loading...
Loading...