Lanosterol (13C3 isotope)

Isotopically labeled sterol intermediate in the cholesterol biosynthesis pathway. Reacts with the dienophile, 4-phenyl-1,2,4-triazoline-3,5-dione (PTAD) to give products that have unique MS fragmentation patterns. This assay increases the sensitivity and shortens the analysis time.

From the laboratory of Ned A. Porter, PhD and Keri A. Tallman, PhD, Vanderbilt University.

Catalog Number Product Size AVAILABILITY Price Qty
EVU135
Lanosterol (13C3 isotope), 1mg
1mg In stock
Price: $500.00
Specifications
Name: Lanosterol-25,26,27-13C3
Chemical Formula: C2713C3H50O
Molecular Weight: 429.71
Format: white powder
Purity: >95%, NMR
Solubility: CHCl3, THF, benzene
Source: synthetic
Isotopic Purity: 95%
Mass Shift: m/z 3
Storage: -20C
Shipped: Ambient temperature
Provider
From the laboratory of Ned A. Porter, PhD and Keri A. Tallman, PhD, Vanderbilt University.
References
  1. The Effect of Small Molecules on Sterol Homeostasis: Measuring 7-Dehydrocholesterol in Dhcr7-Deficient Neuro2a Cells and Human Fibroblasts. Korade, Z.; Kim, H.-Y. H.; Tallman, K. A.; Liu, W.; Koczok, K.; Balogh, I.; Xu, L.; Mirnics, K.; Porter, N. A. J. Medicinal Chemistry 2016, 59, 1102.
  2. A highly sensitive method for analysis of 7-dehydrocholesterol for the study of Smith-Lemli-Opitz syndrome. Liu, W.; Xu, L.; Lamberson, C.; Haas, D.; Korade, Z.; Porter, N. A. J. Lipid Research 2014, 55, 329.

If you publish research with this product, please let us know so we can cite your paper.

 
Loading...
Loading...