Anti-Collagen Alpha-1(I) Chain Carboxy-Propeptide [LF-42] Antibody
![Anti-Collagen Alpha-1(I) Chain Carboxy-Propeptide [LF-42] Antibody](https://www.kerafast.com/MediaStorage/Product/Images/Large/1383_2001202001264513820.jpg "Anti-Collagen Alpha-1(I) Chain Carboxy-Propeptide [LF-42] Antibody")
This rabbit IgG polyclonal antibody was raised against peptide and recognizes human and other species type 1 collagen alpha-1 carboxy propeptide.
Highlights:
- Recognizes human and other species type 1 collagen alpha-1 carboxy propetide - Epitope - amino acid sequence PLDVGAPDQEFGFDVGPVCFL
- Suitable for Immunohistochemistry and Western Blot applications
Collagen is a protein that supports many tissues in the body, including cartilage, bone, tendon, skin and the white part of the eye (sclera). Specifically collagen type 1 alpha 1 encodes the major component of type I collagen, the fibrillar collagen found in most connective tissues, including cartilage. Mutations in the gene can cause ostegensis imperfecta and ehlers-danlos syndrome.
From the laboratory of Larry W. Fisher, PhD, National Institute of Dental and Craniofacial Research/NIH.
This rabbit IgG polyclonal antibody was raised against peptide and recognizes human and other species type 1 collagen alpha-1 carboxy propeptide.
Highlights:
- Recognizes human and other species type 1 collagen alpha-1 carboxy propetide - Epitope - amino acid sequence PLDVGAPDQEFGFDVGPVCFL
- Suitable for Immunohistochemistry and Western Blot applications
Collagen is a protein that supports many tissues in the body, including cartilage, bone, tendon, skin and the white part of the eye (sclera). Specifically collagen type 1 alpha 1 encodes the major component of type I collagen, the fibrillar collagen found in most connective tissues, including cartilage. Mutations in the gene can cause ostegensis imperfecta and ehlers-danlos syndrome.
From the laboratory of Larry W. Fisher, PhD, National Institute of Dental and Craniofacial Research/NIH.
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| Product Type: | Antibody |
| Antigen: | Type I collagen alpha-1 carboxy-propeptide |
| Accession ID: | P02452 |
| Molecular Weight: | 136514 Da |
| Isotype: | IgG |
| Clonality: | Polyclonal |
| Clone Name: | LF-42 |
| Reactivity: | Human and most other species |
| Immunogen: | Peptide |
| Species Immunized: | Rabbit |
| Epitope: | PLDVGAPDQEFGFDVGPVCFL |
| Buffer: | Whole serum |
| Tested Applications: | WB (1:2000), IHC (1:400) |
| Storage: | -80C |
| Shipped: | Cold Packs (Domestic, Overnight); Dry Ice (International) |
- Fisher LW, Stubbs JT 3rd, Young MF. Antisera and cDNA probes to human and certain animal model bone matrix noncollagenous proteins. Acta Orthop Scand Suppl. 1995 Oct;266:61-5.
- Bonfanti L, Mironov AA Jr, Martínez-Menárguez JA, Martella O, Fusella A, Baldassarre M, Buccione R, Geuze HJ, Mironov AA, Luini A. Procollagen traverses the Golgi stack without leaving the lumen of cisternae: evidence for cisternal maturation. Cell. 1998 Dec 23;95(7):993-1003.
- Martínez-Glez V, Valencia M, Caparrós-Martín JA, Aglan M, Temtamy S, Tenorio J, Pulido V, Lindert U, Rohrbach M, Eyre D, Giunta C, Lapunzina P, Ruiz-Perez VL. Identification of a mutation causing deficient BMP1/mTLD proteolytic activity in autosomal recessive osteogenesis imperfecta. Hum Mutat. 2012 Feb;33(2):343-50. doi: 10.1002/humu.21647.
- Tian C, Huang Y, Clauser KR, Rickelt S, Lau AN, Carr SA, Vander Heiden MG, Hynes RO. Suppression of pancreatic ductal adenocarcinoma growth and metastasis by fibrillar collagens produced selectively by tumor cells. Nat Commun. 2021 Apr 20;12(1):2328. View article
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