Anti-Zika Virus Envelope (E) Protein [D1-4G2-4-15] Antibody

This mouse IgG2a monoclonal antibody was generated against flavivirus envelope proteins and recognizes protein E of Zika virus.

Highlights:

  • Recognizes Zika virus
  • Suitable for Immunofluorescence applications

Zika virus (ZIKV) is a member of the virus family Flaviviridae and the genus Flavivirus, transmitted by daytime-active Aedes mosquitoes. Zika is related to other mosquito transmitted viruses such as dengue, yellow fever, Japanese encephalitis and west nile. Similar to other flaviviruses, ZIKV is enveloped and icosahedral and has a nonsegmented, single-stranded, positive-sense RNA genome. Common symptoms of infection with the virus include mild headaches, maculopapular rash, fever, malaise, conjunctivitis, and joint pains.

Catalog Number Product Size AVAILABILITY Price Qty
FCG006
Anti-Zika Virus Envelope (E) Protein [D1-4G2-4-15] Antibody, 100ug
100ug In stock
Price: $360.00
Specifications
Antigen: Flavivirus Envelope (E) Protein
Isotype: IgG2a
Clonality: Monoclonal
Clone Name: D1-4G2-4-15
Reactivity: Virus
Immunogen: Flavivirus envelope proteins
Species Immunized: Mouse
Purification Method: Protein G
Buffer: PBS, pH 7.2
Tested Applications: IF
Comments: Derived from strain YYC202, strain has a growth requirement for acetate and isoleucine
Storage: -20C
Shipped: Cold packs
Data

Detection of ZIKV via immunofluorescence

Sample confocal images of forebrain-specific hNPCs 56 hr after infection with ZIKV supernatant, immunostained for ZIKV envelop protein (ZIKVE; green) and DAPI (gray). Cells were differentiated from the C1-2 hiPSC line. Scale bars, 20 ?m.

Adapted from: Tang H, et al. Cell Stem Cell. 2016 May 5;18(5):587-90.

References
  1. Tang H, Hammack C, Ogden SC, Wen Z, Qian X, Li Y, Yao B, Shin J, Zhang F, Lee EM, Christian KM, Didier RA, Jin P, Song H, Ming GL. Zika Virus Infects Human Cortical Neural Progenitors and Attenuates Their Growth. Cell Stem Cell. 2016 May 5;18(5):587-90.

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