Anti-Tetraspanin-8 (Tspan8) [CO-029] Antibody
![Anti-Tetraspanin-8 (Tspan8) [CO-029] Antibody](https://www.kerafast.com/MediaStorage/Product/Images/Large/1175_2001202001263711740.jpg "Anti-Tetraspanin-8 (Tspan8) [CO-029] Antibody")
This mouse IgG monoclonal antibody was generated against carcinoma cells and recognizes human Tetraspanin-8 (Tspan8).
Highlights:
- Specific for human Tspan8
- Suitable for Western Blot and Immunofluorescence applications
CO-029/TSPAN8 is a glycoprotein and a member of transmembrane 4 superfamily, also known as the tetraspanin family. CO-029/TSPAN8 is a cell-surface protein that is characterized by the presence of four hydrophobic domains. CO-029/TSPAN8 controls signaling regulation of cell development, activation, growth and motility. CO-029/TSPAN8 also forms a complex with integrins and is expressed in various carcinomas.
From the laboratory of Meenhard Herlyn, DVM, DSc, The Wistar Institute.
Part of The Investigator's Annexe program.
This mouse IgG monoclonal antibody was generated against carcinoma cells and recognizes human Tetraspanin-8 (Tspan8).
Highlights:
- Specific for human Tspan8
- Suitable for Western Blot and Immunofluorescence applications
CO-029/TSPAN8 is a glycoprotein and a member of transmembrane 4 superfamily, also known as the tetraspanin family. CO-029/TSPAN8 is a cell-surface protein that is characterized by the presence of four hydrophobic domains. CO-029/TSPAN8 controls signaling regulation of cell development, activation, growth and motility. CO-029/TSPAN8 also forms a complex with integrins and is expressed in various carcinomas.
From the laboratory of Meenhard Herlyn, DVM, DSc, The Wistar Institute.
Part of The Investigator's Annexe program.
Specifications
| Product Type: | Antibody |
| Alternative Name(s): | Tetraspanin-8, Tspan-8,Transmembrane 4 superfamily member 3 Tumor-associated antigen CO-029 |
| Antigen: | CO-029 or TSPAN8 |
| Accession ID: | P19075 |
| Molecular Weight: | 27-34 kDa |
| Isotype: | IgG |
| Clonality: | Monoclonal |
| Clone Name: | CO-029 |
| Reactivity: | Human |
| Immunogen: | Carcinoma cells |
| Species Immunized: | Mouse |
| Epitope: | CO-029 recognizes TSPAN8, a cell surface glycoprotein |
| Purification Method: | Protein G |
| Buffer: | 0.1M Sodium Phosphate, pH 7.4, 0.15M NaCl, 0.05% (w/v) Sodium Azide |
| Tested Applications: | WB (1:1000), IF (1:50) |
| Concentration: | 1.93mg/mL |
| Storage: | -20C |
| Shipped: | Cold packs |
Provider
From the laboratory of Meenhard Herlyn, DVM, DSc, The Wistar Institute.
References
- Koprowski H, Steplewski Z, Mitchell K, Herlyn M, Herlyn D, Fuhrer P. Colorectal carcinoma antigens detected by hybridoma antibodies. Somatic Cell Genet. 1979 Nov;5(6):957-71.
- Szala S, Kasai Y, Steplewski Z, Rodeck U, Koprowski H, Linnenbach AJ. Molecular cloning of cDNA for the human tumor-associated antigen CO-029 and identification of related transmembrane antigens. Proc Natl Acad Sci U S A. 1990 Sep;87(17):6833-7.
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