Anti-IRX5 Antibody

This IgG rabbit polyclonal antibody is reactive against human, mouse and rat IRX5.

Highlights:

  • Broad cross reactivity - Human, Mouse and Rat
  • Suitable for Western Blot applications

Iroquouis homeobox (IRX) factors are a family of homeodomain transcription factors that contribute to many different cells in the body including brain, other organs and fat cells. Specifically, IRX5 (part of the Irxb subgroup) has be shown to be expressed in endocardium lining the ventricular and atrial myocardium.

From the laboratory of Chi-chung Hui, PhD, Hospital for Sick Children.

The Investigator's Annexe Part of The Investigator's Annexe program.

Catalog Number Product Size AVAILABILITY Price Qty
ESK402
Anti-IRX5 Antibody, 100uL
100uL In stock
Price: $295.00
Specifications
Product Type: Antibody
Antigen: Irx5
Accession ID: NP_061296
Molecular Weight: 53 kDa
Isotype: IgG
Clonality: Polyclonal
Reactivity: Human, mouse and rat
Immunogen: Recombinant Protein
Species Immunized: Rabbit
Buffer: Antiserum contains 0.02% Thimersol
Tested Applications: WB (1:1000)
Storage: -20C
Shipped: Cold packs
Data

Western Blot for Irx5 Expression

Western blot showing Irx5 expression in nuclear extract from epicardial myocardium (lane 1), endocardial myocardium (lane 2), isolated myocytes from epicardial myocardium (lane 3), isolated myocytes from endocardial myocardium (lane 4), isolated neonatal myocytes (lane 5), isolated myocytes from Irx5?/? epicardial myocardium (lane 6), and isolated myocytes from Irx5?/? endocardial myocardium (lane 7). GAPDH is shown as loading control.

Adapted from: Costantini DL, et al. Cell. 2005 Oct 21;123(2):347-58.

Provider
From the laboratory of Chi-chung Hui, PhD, Hospital for Sick Children.
References
  1. Costantini DL, Arruda EP, Agarwal P, Kim K-H, Zhu Y, Zhu W, Lebel M, Cheng CW, Park CY, Pierce SA, Guerchicoff A, Pollevick GD, Chan TY, Kabir G, Cheng SH, Husain M, Antzelevitch C, Srivastava D, Gross GJ, Hui C-c, Backx PH, Bruneau B. The homeodomain transcription factor Irx5 establishes the mouse cardiac ventricular repolarization gradient. Cell. 2005 Oct 21;123(2):347-58.

If you publish research with this product, please let us know so we can cite your paper.

 
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