Anti-IRX3 Antibody

This IgG rabbit polyclonal antibody is reactive against human, mouse and rat IRX3.

Highlights:

  • Broad cross reactivity - Human, Mouse and Rat
  • Suitable for Western Blot, Immunoprecipitation, Immunohistochemistry and Iimmunofluorescence applications

Iroquouis homeobox (IRX) factors are a family of homeodomain transcription factors that contribute to many different cells in the body inlcuding brain, other organs and fat cells. Specifically, IRX3 (part of the Irxb subgroup) controls a group of neurons in the brain that activates brown fat to increase energy expenditure, playing an essential role in obesity.

From the laboratory of Chi-chung Hui, PhD, Hospital for Sick Children.

The Investigator's Annexe Part of The Investigator's Annexe program.

Catalog Number Product Size AVAILABILITY Price Qty
ESK401
Anti-IRX3 Antibody, 100uL
1 vial In stock
Price: $295.00
Specifications
Antigen: Irx3
Accession ID: NP_032419
Molecular Weight: 56 kDa
Isotype: IgG
Clonality: Polyclonal
Reactivity: Human, mouse and rat
Immunogen: Recombinant Protein
Species Immunized: Rabbit
Buffer: Antiserum contains 0.02% Thimersol
Tested Applications: WB (1:1000), IP, IF, IHC
Storage: -20C
Shipped: Cold packs
Provider
From the laboratory of Chi-chung Hui, PhD, Hospital for Sick Children.
References
  1. Smemo S, Tena JJ, Kim KH, Gamazon ER, Sakabe NJ, Gómez-Marín C, Aneas I, Credidio FL, Sobreira DR, Wasserman NF, Lee JH, Puviindran V, Tam D, Shen M, Son JE, Vakili NA, Sung HK, Naranjo S, Acemel RD, Manzanares M, Nagy A, Cox NJ, Hui CC, Gomez-Skarmeta JL, Nóbrega MA. Obesity-associated variants within FTO form long-range functional connections with IRX3. Nature. 2014 Mar 20;507(7492):371-5.

If you publish research with this product, please let us know so we can cite your paper.

 
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