Anti-IRF3 [17C2] Antibody
![Anti-IRF3 [17C2] Antibody](https://www.kerafast.com/MediaStorage/Product/Images/Large/748_200120200126207470.jpg "Anti-IRF3 [17C2] Antibody")
This monoclonal antibody was generated against purified recombinant human interferon regulatory factor 3 (IRF3) and is specific for human IRF3.
IRF3 is a member of the interferon regulatory transcription factor (IRF) family. IRF3 has been shown to contain several functional domains including a nuclear export signal, a DNA-binding domain, a C-terminal IRF association domain and several regulatory phosphorylation sites. IRF3 plays an important role in the innate immune system's response to viral infection.
From the laboratory of Adolfo Garcia-Sastre, PhD, Icahn School of Medicine at Mount Sinai.
Part of The Investigator's Annexe program.
This monoclonal antibody was generated against purified recombinant human interferon regulatory factor 3 (IRF3) and is specific for human IRF3.
IRF3 is a member of the interferon regulatory transcription factor (IRF) family. IRF3 has been shown to contain several functional domains including a nuclear export signal, a DNA-binding domain, a C-terminal IRF association domain and several regulatory phosphorylation sites. IRF3 plays an important role in the innate immune system's response to viral infection.
From the laboratory of Adolfo Garcia-Sastre, PhD, Icahn School of Medicine at Mount Sinai.
Part of The Investigator's Annexe program.
Specifications
| Product Type: | Antibody |
| Antigen: | Human IRF3 |
| Accession ID: | Q14653 |
| Molecular Weight: | 47.2 kDa |
| Isotype: | IgG2a |
| Clonality: | Monoclonal |
| Clone Name: | 17C2 |
| Reactivity: | Human |
| Immunogen: | Recombinant protein derived from the C-terminal region of human IRF3 |
| Species Immunized: | Mouse |
| Purification Method: | Protein A |
| Tested Applications: | WB (1:1000), ELISA, IF (1:200), IHC |
| Concentration: | 1 mg/mL |
| Storage: | -20C |
| Shipped: | Cold packs |
Provider
From the laboratory of Adolfo Garcia-Sastre, PhD, Icahn School of Medicine at Mount Sinai.
References
- Garcia-Sastre, et al. Manuscript in progress.
- Mathers C, Schafer X, Martínez-Sobrido L, Munger J. The human cytomegalovirus UL26 protein antagonizes NF-κB activation. J Virol. 2014 Dec;88(24):14289-300. doi: 10.1128/JVI.02552-14. PubMed PMID: 25275128; PubMed Central PMCID: PMC4249132. View Article
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