10-Gingerol

10-Gingerol is isolated from the rhizomes or roots of the plant Zingiber officinale (ginger).

10-Gingerol is one of several active compounds isolated from the ginger root. 10-Gingerol is believed to inhibit the anti-serotonin 3 receptor function leading to anti-emetic properties. Additionally, it has been shown to affect gastric motility and potentially have an antispasmodic effect on the gastrointestinal system.

Catalog Number Product Size AVAILABILITY Price Qty
FAP035
10-Gingerol, 5mg
5mg 1-2 weeks
Price: $164.50
FAP036
10-Gingerol, 25mg
25mg 1-2 weeks
Price: $658.00
Specifications
Chemical Formula: C21H34O4
CAS number: 23513-15-7
Molecular Weight: 350.49
Format: Light yellow powder
Purity: >98 % determined by HPLC
Solubility: Soluble in methanol and ethanol
Stability: Stable over extended period at -20C.
Storage: -20C, avoid exposure to oxygen and direct sunlight
Shipped: Cold Pack
Data

10-Gingerol HPLC Chromatogram.


Purification Notes: Purification is conducted using near-critical and super-critical fluids during extraction from the ginger root.

References
  1. Ali B, Blunden G, Tanira M and Nemmar A. (2008). Some phytochemical, pharmacological and toxicological properties of ginger (Zingiber officinale Roscoe): A review of recent research. Food and Chemical Toxicology. 46(2): 409-420.
  2. Blumenthal M, Busse W, Goldberg A, Gruenwald J, Hall T, Klein S, Riggins C and Rister R. (1998). The Complete German Commission E monographs. Therapeutic Guide to Herbal Medicines, Austin TX, American Botanical Council.
  3. Chaiyakunapruk N, Kitikannakorn N, Nathisuwan S, Leeprakobboon K and Leelasettagool C. (2006). The efficacy of ginger for the prevention of postoperative nausea and vomiting: a meta-analysis. Am. J. Obstet. Gynecol. 194, 95–99.
  4. Chen C, Kuo M, Wu C and Ho C. (1986). Pungent Compounds of Ginger (Zingiber officinale Roscoe) Extracted by Liquid Carbon Dioxide. Journal of Agriculture and Food Chemistry 34(3): 477-480.
  5. Hashimoto K, Satoh K, Murata P, Makino B, Sakakibara I, Kase Y, Ishige A, Higuchi M and Sasaki H. (2002). Component of Zingiber officinale that improves the enhancement of small intestinal transport. Planta Medica. 68:936-9.
  6. Huang Q, Iwamoto M, Aoki S, Tanaka N, Tajima K, Yamahara J, Takaishi Y, Yoshida M, Tomimatsu T and Tamai Y. (1991). Anti-5-hydroxytryptamine 3 effect of galanolactone, diterpenoid isolated from ginger. Chem. Pharm. Bull. (Tokyo) 39, 397–399.
  7. Suekawa M, Ishige A, Yuasa K, Sudo K, Aburada M and Hosoya E. (1984). Pharmacological studies on ginger: I. Pharmacological action of pungent constituents, (6)-gingerol and (6)-shogaol. J Pharmacobiodyn. 7:836-48.
  8. Yamahara J, Rong H, Iwamoto M, Kobayashi G, Matsuda H and Fujimura H. (1989). Active components of ginger exhibiting anti-serotonergic action. Phytother. Res. 3, 70–71.

If you publish research with this product, please let us know so we can cite your paper.

 
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