Anti-p400 Antibody (Serum)
This antibody was raised in rabbits against the p400 C-terminal peptide (SSDSPSQQPKLQMRVPAVRLKTPTKPP) and is recommended for detection of human p400 by Western blot.
E1A-binding protein p400 is a component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histones H4 and H2A. p400 belongs to the SWI2/SNF2 family of ATPases and is found in two highly related chromatin remodelling complexes : the Tip60 and p400 complexes. It has been implicated in cell cycle control, apoptosis and development.
From the laboratory of John Chrivia, PhD, St. Louis University.
Part of The Investigator's Annexe program.
This antibody was raised in rabbits against the p400 C-terminal peptide (SSDSPSQQPKLQMRVPAVRLKTPTKPP) and is recommended for detection of human p400 by Western blot.
E1A-binding protein p400 is a component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histones H4 and H2A. p400 belongs to the SWI2/SNF2 family of ATPases and is found in two highly related chromatin remodelling complexes : the Tip60 and p400 complexes. It has been implicated in cell cycle control, apoptosis and development.
From the laboratory of John Chrivia, PhD, St. Louis University.
Part of The Investigator's Annexe program.
| Product Type: | Antibody |
| Accession ID: | Q96L91 |
| Antigen: | p400 (human domino ortholog) |
| Molecular Weight: | 400 kDa |
| Isotype: | IgG |
| Clonality: | Polyclonal |
| Clone Name: | SLU3 |
| Reactivity: | Human (use with other species has not been tested) |
| Immunogen: | Peptide |
| Species Immunized: | Rabbit |
| Epitope: | C-terminal peptide |
| Purification Method: | Crude serum |
| Buffer: | Normal rabbit serum |
| Tested Applications: | WB (1:1000-3000) |
| Amount: | 100uL |
| Storage: | -80C |
| Shipped: | Cold packs |
Western Blot Analysis.
Western blot analysis of A549 nuclear extracts were performed using anti-p400 antibody (SLU3) or in the right panel using anti-SRCAP antibody (SLU2).
- Bowman TA, Wong MW, Cox LK, Baldassare JJ and Chrivia JC. Loss of H2A.Z is not sufficient to determine the transcriptional activity of SNF2-Related CBP Activator Protein (SRCAP) or p400 complexes. International Journal of Cell Biology . :715642. Epub 2011 May 29.
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