Human IgE Lambda Protein
IgE is the least abundant immunoglobulin (Ig) but it has a central role in allergic diseases. Blood serum IgE levels in a normal ("non-atopic") individual are ~150 ng/ml, compared to 10 mg/ml for the Igs. IgE binds to various immune cells, and upon allergic recognition, it can trigger an inflammatory response from those cells. Most IgE research has been centered around the mechanism of a form of allergy known as type 1 hypersensitivity. Additionally, IgE may be an important target in treatments for allergy and asthma. Some recent investigations have led to suggestions that IgE is involved in recognition of cancer.
From the laboratory of Kenneth H. Roux, PhD, Florida State University.
Part of The Investigator's Annexe program.
| Catalog Number |
Product |
Description |
Price |
Order |
| EX0010 |
Human IgE Protein, 100ug
|
1 mg/mL |
Price: $174.00
|
|
| EX0011 |
Human IgE Protein, 500ug
|
1 mg/mL |
Price: $457.00
|
|
| Peptide: |
Human IgE Lambda Protein |
| Molecular Weight: |
188 kDa |
| Concentration: |
1 mg/mL |
| Special Characteristic(s): |
Purified from original US IgE myeloma patient (patient PS) |
| Quality: |
Single band by SDS-PAGE |
| Source: |
Human serum |
| Physical Form (Storage Buffer): |
Purified stable protein in PBS, pH 7.4, 0.1% NaN3 |
| Storage Conditions: |
-20 C long term, 4C short term |
| Shipped: |
Cold pack |
Comments
Purified by DEAE chromatography. In PBS with 0.1% NaN3.
Original serum has been tested for human pathogens. Negative for HBsAg, HCV, HBc, HIV-1/2 and HTLV-I/II
References
- Salmon et al., IgE myeloma: Total body tumor cell number and synthesis of IgE and DNA. Blood 37: 696-705. 1971.
- Ogawa et al. Clinical aspects of IgE myeloma. New England Journal of Medicine. 281: 1217 - 1220. 1969.
If you publish research with this product, please let us know so we can cite your paper.
