FcγRI (CD64) Expressing CHO Cell Line (mRG1)
CHO cell line expressing the mouse Fc-gamma receptor 1 (FcγRI) alpha chain for antigen presentation receptor studies.
Highlights:
- Expresses FcγRI alpha chain
- Effective model system for inducing B cell activation
Fc-gamma receptor 1 (FcγRI) also known as CD64 or Cluster of Differentiation 64 is an integral membrane protein known as the Fc receptor that binds to IgG type antibodies. The receptor is important in signaling cellular activation or signal transduction in immune cells, specifically macrophages and monocytes.
From the laboratory of Daniel H. Conrad, PhD, Virginia Commonwealth University.
CHO cell line expressing the mouse Fc-gamma receptor 1 (FcγRI) alpha chain for antigen presentation receptor studies.
Highlights:
- Expresses FcγRI alpha chain
- Effective model system for inducing B cell activation
Fc-gamma receptor 1 (FcγRI) also known as CD64 or Cluster of Differentiation 64 is an integral membrane protein known as the Fc receptor that binds to IgG type antibodies. The receptor is important in signaling cellular activation or signal transduction in immune cells, specifically macrophages and monocytes.
From the laboratory of Daniel H. Conrad, PhD, Virginia Commonwealth University.
Specifications
| Product Type: | Cell Line |
| Name: | mRG1 |
| Cell Type: | CHO |
| Accession ID: | P12314, CVCL_HC53 |
| Organism: | Hamster |
| Morphology: | Fibroblast |
| Biosafety Level: | 1 |
| Growth Conditions: | GMEM, FBS (dialyzed), L-Glutamate/L-Aspargine, NEAA, Sodium pyruvate, Nucleoside mix, Pen/Strep, plasmocin-Normacin combo (Invivogen) |
| Cryopreservation: | Synth-a-Freeze® Cryopreservation Medium (Gibco Cat. A1254201) |
| Storage: | Liquid nitrogen |
| Shipped: | Dry ice |
Documentation
Provider
From the laboratory of Daniel H. Conrad, PhD, Virginia Commonwealth University.
References
- Cho S, Conrad DH. A new multivalent B cell activation model--anti-IgD bound to Fc gamma RI: properties and comparison with CD40L-mediated activation. Int Immunol. 1997 Feb;9(2):239-48.
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