Anti-Phosphotyrosine [6G9] Antibody
![Anti-Phosphotyrosine [6G9] Antibody](https://www.kerafast.com/MediaStorage/Product/Images/Large/979_200120200126299780.jpg "Anti-Phosphotyrosine [6G9] Antibody")
This IgG2a mouse monoclonal antibody [6G9] was generated against tyrosine phosphoproteins purified from chicken embryonic fibroblasts (CEFs) expressing pp60/c-src 527F and 2A/527F and is reactive against chicken, hamster, human, mouse and rat phospho-tyrosine.
Highlights
- Reacts with chicken, hamster, human, mouse and rat phospho-tyrosine
- Suitable for Western Blot and Immunoprecipitation applications
Phosyphorylation is a common modification of proteins that can alter their function, such as protein-protein interaction, protein half- life and cellular localization. Specifically, phosphorylation of tyrosines has been shown to be part of oncogenic transformation, cell cycle and signal transduction during mitogenesis.
From the laboratories of J. Thomas Parsons, PhD, Sarah (Sally) J. Parsons, PhD, and Albert B. Reynolds, PhD, University of Virginia.
Part of The Investigator's Annexe program.
This IgG2a mouse monoclonal antibody [6G9] was generated against tyrosine phosphoproteins purified from chicken embryonic fibroblasts (CEFs) expressing pp60/c-src 527F and 2A/527F and is reactive against chicken, hamster, human, mouse and rat phospho-tyrosine.
Highlights
- Reacts with chicken, hamster, human, mouse and rat phospho-tyrosine
- Suitable for Western Blot and Immunoprecipitation applications
Phosyphorylation is a common modification of proteins that can alter their function, such as protein-protein interaction, protein half- life and cellular localization. Specifically, phosphorylation of tyrosines has been shown to be part of oncogenic transformation, cell cycle and signal transduction during mitogenesis.
From the laboratories of J. Thomas Parsons, PhD, Sarah (Sally) J. Parsons, PhD, and Albert B. Reynolds, PhD, University of Virginia.
Part of The Investigator's Annexe program.
| Product Type: | Antibody |
| Antigen: | Phospho-tyrosine |
| Isotype: | IgG2a |
| Clonality: | Monoclonal |
| Clone Name: | 6G9 |
| Reactivity: | Chicken, hamster, human, mouse and rat |
| Immunogen: | Tyrosine phosphoproteins purified from chicken embryonic fibroblasts (CEFs) expressing pp60/c-src 527F and 2A/527F |
| Species Immunized: | Mouse |
| Purification Method: | Protein G Affinity Chromatography |
| Buffer: | PBS, 0.05% (w/v) Sodium Azide |
| Tested Applications: | WB, IP |
| Storage: | -20C |
| Shipped: | Cold packs |
- Kanner SB, Reynolds AB, Vines RR, Parsons JT. Monoclonal antibodies to individual tyrosine-phosphorylated protein substrates of oncogene-encoded tyrosine kinases.Proc Natl Acad Sci U S A. 1990 May;87(9):3328-32.
If you publish research with this product, please let us know so we can cite your paper.
