COVID-19/SARS-CoV Nucleoprotein [CR3009 (03-009)] Antibodies

Recombinant monoclonal antibody to COVID-19 & SARS-CoV Nucleoprotein.

Highlights:

  • Choose from human IgG1 or rabbit IgGk formats
  • Manufactured using Absolute Antibody’s Recombinant Platform with variable regions (i.e., specificity) from the hybridoma CR3009
  • Chimeric rabbit antibody was made using the variable domain sequences of the original Human IgG1 format, for improved compatibility with existing reagents, assays and techniques

From our sister company Absolute Antibody.

Catalog Number Product DataSheet Size AVAILABILITY Price Qty
Kf-Ab01691-10.0
Anti-COVID-19/SARS-CoV Nucleoprotein [CR3009 (03-009)] Human IgG1k Antibody
200ug In stock
Regular Price:$470.00
On Sale:
Kf-Ab01691-23.0
Anti-COVID-19/SARS-CoV Nucleoprotein [CR3009 (03-009)] Rabbit IgGk Antibody
200ug In stock
Regular Price:$470.00
On Sale:

For larger sizes, please Contact Us for a bulk discount.

Specifications

Product Type: Antibody
Name: Anti-COVID-19/SARS-CoV Nucleoprotein [CR3009 (03-009)]
Alternative Name(s): NP; NC; Protein N; Nucleocapsid protein; SARS-CoV Protein N; SARS-CoV Nucleocapsid protein; SARS Coronavirus; SARS-CoV-2; SARS CoV 2; 2019-nCoV
Antigen: COVID-19/SARS-CoV Nucleoprotein
Accession ID: P0DTC9
Source: Recombinant
Isotype: Human IgG1k or Rabbit IgGk
Clonality: Monoclonal
Clone Name: CR3009 (03-009)
Reactivity: SARS-CoV-2 (COVID-19) and SARS Coronavirus
Specificity: This antibody recognizes and binds the non-linear/conformational epitope of the N protein of SARS CoV and also binds the SARS CoV2 nucleoprotein.
Immunogen: The original antibody was generated by cloning the variable regions of the scFvs selected from phage display libraries into separate vectors for IgG1 heavy-chain and light-chain expression. The harvested supernatents were then purified on protein A columns.
Purification Method: Protein A
Buffer: PBS, 0.02% Proclin 300
Tested Applications: ELISA, IF
Concentration: 1 mg/mL
Storage: Store at +4C for up to 3 months. For longer storage, aliquot and store at -20C.
Shipped: Cold packs

Provider
From our sister company Absolute Antibody.
Comments
This antibody is recommended for detection of SARS CoV2 protein N (nucleoprotein). This antibody binds both the nucleocapsid protein of the SARS-CoV and SARS CoV-2 (2019-nCoV). Initial characterization of the antibody for binding to 2019-nCoV was done using ELISA. This antibody shows potential to be used for development of diagnostic assays. Various isotype versions of the antibody namely human IgG1, IgG3, IgM, IgA and the less common IgG2 and IgG4 are available for the investigation of their role in response to SARS CoV2. Competitive ELISA of this antibody with CR3018 suggests that both these antibodies bind different epitopes of the N protein of SARS CoV. Thus, a combination of these two antibodies is suggested for virus capture assays. Immunofluorescence staining was used to demonstrate binding of CR3009 to SARS-CoV infected Vero cells. (PMID:15650189).
References
  1. van den Brink EN, Ter Meulen J, Cox F, et al. Molecular and biological characterization of human monoclonal antibodies binding to the spike and nucleocapsid proteins of severe acute respiratory syndrome coronavirus. J Virol. 2005;79(3):1635_1644.

If you publish research with this product, please let us know so we can cite your paper.

Loading...